Trials / Terminated
TerminatedNCT00560625
Does Inhaled Busedonide or Fluticasone Impair Adrenal Function?
Low Dose(1mcg) ACTH Stimulation Test for Assessment of the Hypothalamus-pituitary-adrenal Axis in Patients Treated With Inhaled Busedonide or Fluticasone.
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (estimated)
- Sponsor
- HaEmek Medical Center, Israel · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
Inhaled corticosteroids are largely used in patients with asthma or chronic obstructive lung diseases. The purpose of this study is to determine if the use of inhaled corticosteroids is associated with suppression of endogenous cortisol production, as seen in patients treated with pharmacologic doses of oral or parenteral steroids.
Detailed description
The normalcy of the hypothalmic-pituitary-adrenal (HPA) axis of enrolled subjects will be assessed by low dose (1mcg) corticotropin (ACTH)stimulation test. Serum cortisol levels will be measured before , 30 minutes and 60 minutes after 1 mcg ACTH intravenous injection.
Conditions
Timeline
- Start date
- 2007-05-01
- Primary completion
- 2007-12-01
- Completion
- 2008-12-01
- First posted
- 2007-11-20
- Last updated
- 2016-09-08
Locations
1 site across 1 country: Israel
Source: ClinicalTrials.gov record NCT00560625. Inclusion in this directory is not an endorsement.