NCT00556387

Efficacy of Ketamine in Children With Severe Brain Injury for Brain Cell Protection

Possible Neuroprotective Effects of Ketamine in Children With Severe Traumatic Brain Injury

• Status: Withdrawn
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Arkansas · Academic / Other
• Sex: All
• Age: 1 Month – 16 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the possible effects of an anesthetic agent called Ketamine on the injured brain in children. The researchers think that it will effect the outcomes of children with these injuries.

Conditions

• Traumatic Brain Injury

Interventions

Type	Name	Description
DRUG	saline	1 mg/kg IV bolus slowly over 1-2 minutes followed by 0.5 mg/kg IV continuous infusion over 48 hours or until discontinuation of ICP monitor (whichever occurs first)
DRUG	Ketamine	1 mg/kg IV bolus slowly over 1-2 minutes, followed by 0.5 mg/kg IV continuous infusion for 48 hours or until discontinuation of ICP monitor (whichever occurs first)

Timeline

• Start date: 2008-12-01
• Primary completion: 2012-12-01
• Completion: 2012-12-01
• First posted: 2007-11-12
• Last updated: 2013-11-01