Trials / Completed
CompletedNCT00549536
The Effect of Calcium Supplementation on Insulin Resistance and 24h Blood Pressure
The Effect of Oral Calcium Supplementation on Insulin Sensitivity, Intracellular Cationic Concentrations and the Transmembrane Sodium/Hydrogen Exchanger Activity in Subjects With Type 2 Diabetes and Hypertension
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 31 (actual)
- Sponsor
- Aristotle University Of Thessaloniki · Academic / Other
- Sex
- All
- Age
- 18 Years – 85 Years
- Healthy volunteers
- Not accepted
Summary
Increased levels of intracellular calcium are thought to diminish maximal cellular response to insulin and induce insulin resistance. Also, both hypertension and diabetes are thought to be conditions of altered intracellular ionic state. The aim of the present study is to investigate the possible effect of oral calcium supplementation on intracellular ions, insulin sensitivity, 24-h blood pressure and sodium/hydrogen exchanger activity in patients with type 2 diabetes and essential hypertension.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | tablets each containing of 1000mg elemental calcium (Mega-Calcium Sandoz) | 1500 mg of elemental calcium per day. |
Timeline
- Start date
- 2007-01-01
- Primary completion
- 2008-05-01
- Completion
- 2008-05-01
- First posted
- 2007-10-26
- Last updated
- 2008-07-04
Locations
1 site across 1 country: Greece
Source: ClinicalTrials.gov record NCT00549536. Inclusion in this directory is not an endorsement.