Trials / Unknown
UnknownNCT00522496
Proteomics of Severe Traumatic Brain Injury: A Feasibility Study
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 8 (estimated)
- Sponsor
- University of Calgary · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to: 1. Determine the temporal course of matrix metalloproteinase (MMP) expression in patients wiht severe traumatic brain injury 2. Determine the temporal course of the expression of MMP-related inflammatory mediators of secondary injury in patients with severe traumatic brain injury 3. Describe the association of physiological changes and standard microdialysis analyte measures (lactate, pyruvate, lactate/pyruvate ratio, and glucose) to MMP and neuroinflammatory marker concentrations.
Conditions
Timeline
- Start date
- 2007-07-01
- Completion
- 2009-08-01
- First posted
- 2007-08-29
- Last updated
- 2009-02-24
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT00522496. Inclusion in this directory is not an endorsement.