NCT00511979

Comparison of the Effect on the Glucose Infusion Rates Between Inhaled Technosphere Insulin and a Subcutaneous Injection of Regular Human Insulin

Effect of Different Doses of Inhaled Technosphere Insulin on Glucose Infusion Rates During Euglycemic Clamps in Comparison to a Subcutaneous Injection of Regular Human Insulin

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Mannkind Corporation · Industry
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

A prospective, single center, open randomized, six way crossover study comparing the dose response effect of four different doses of Technosphere Insulin after pulmonary function delivery in comparison to s.c. injection of two different doses of regular human insulin.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Technosphere Insulin
DRUG	Technosphere insulin
DRUG	Technosphere insulin
DRUG	Regular human insulin

Timeline

• Start date: 1999-08-01
• Primary completion: 2000-02-01
• Completion: 2000-06-01
• First posted: 2007-08-06
• Last updated: 2012-06-26