NCT00485147

Locomotion and Global Positioning System in Arterial Disease

Study of Human Locomotion With Global Positioning System. Application to Patients With Peripheral Arterial Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 140 (actual)
• Sponsor: University Hospital, Angers · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The maximal walking distance (MWD) performed on treadmill (TT) remains the gold standard in estimating the walking capacity of patients suffering from peripheral arterial disease (PAD) with intermittent claudication, although treadmills are not accessible to most physicians. We hypothesized that global positioning system (GPS) recordings could monitor community-based outdoor walking and provide valid information on walking capacity in PAD patients.

Detailed description

The study has two main objectives, conducted together. Each objective include several phases. Objective 1: technical validation of GPS measurements in healthy subjects. phase 1: technical validation of a GPS device to study outdoor walking (completed). phase 2: comparison and use of various GPS devices (intra- and inter-GPS variability) in the study outdoor walking (on-going). phase 3: study of several factors that could influence accuracy of GPS measurements as walking speed, environment, sampling frequency and others technical features as the WAAS/EGNOS function (on-going). Objective 2: Application in PAD patients to study walking capacity under free-living conditions phase 1: comparison of GPS measurements (maximal walking distance) with the gold standard treadmill measurement of maximal walking distance (completed). phase 2: analysis of the variability of the walking capacity under free-living conditions from GPS measurements (completed). phase 3: study of reliability and sensibility (effect of treatment) of GPS measurements (on-going). phase 4: study of the relationship between laboratory measurements of walking capacity and GPS-derived parameters.

Conditions

• Peripheral Arterial Disease

Interventions

Type	Name	Description
PROCEDURE	Recording of GPS during a free walking in a public park	Analyse the clinical change after surgery from GPS measurements and compare it with laboratory measurement.

Timeline

• Start date: 2006-03-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2007-06-12
• Last updated: 2012-07-02

Locations

1 site across 1 country: France