Clinical Trials Directory

Trials / Terminated

TerminatedNCT00458861

BG9924 in Combination With Methotrexate for Participants With Active Rheumatoid Arthritis

A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy, Safety, PK, and PD of BG9924 When Given in Combo With MTX to Subjects With Active RA Who Have Had an Inadequate Response to Anti-TNF

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
115 (actual)
Sponsor
Biogen · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This Phase 2b study is designed to evaluate the efficacy and safety of BG9924 given subcutaneously (SC) versus placebo in participants with active rheumatoid arthritis (RA) who have previously had an inadequate response to treatment with anti-tumor necrosis factor (anti-TNF) therapy.

Conditions

Interventions

TypeNameDescription
BIOLOGICALBG9924Subcutaneous administration of BG9924 given every other week for 12 weeks
OTHERPlacebo ComparatorSubcutaneous administration of placebo given every other week for 12 weeks

Timeline

Start date
2007-03-01
Primary completion
2008-10-01
Completion
2008-10-01
First posted
2007-04-11
Last updated
2016-01-21

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00458861. Inclusion in this directory is not an endorsement.