Trials / Completed
CompletedNCT00454961
Effectiveness of Artemether-Lumefantrine for Malaria Treatment of Children at Community Level in Tanzania
Effectiveness of Artemether-Lumefantrine Treatment Provided by Community Health Worker Against Uncomplicated Malaria in Children Under 5 Years of Age in Tanzania
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- Sponsor
- Karolinska University Hospital · Academic / Other
- Sex
- All
- Age
- 5 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this clinical trial is to assess the effectiveness of artemether-lumefantrine (Coartem®) treatment provided by community health workers against uncomplicated malaria in children under 5 years of age in Kibaha District, Tanzania, during an extended follow-up of 42 days. The hypothesis is that artemether-lumefantrine treatment provided by community health workers will result in less than 85% PCR-corrected parasitological effectiveness by day 42, mainly due to partial non-compliance to full standard 6-dose regimen of the drug.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | artemether-lumefantrine |
Timeline
- Start date
- 2007-04-01
- First posted
- 2007-04-02
- Last updated
- 2007-10-25
Locations
1 site across 1 country: Tanzania
Source: ClinicalTrials.gov record NCT00454961. Inclusion in this directory is not an endorsement.