Trials / Unknown
UnknownNCT00453752
Non-Invasive Diagnostic and Functional Evaluation of Cardiac Involvement in Patients With Systemic Sclerosis
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (planned)
- Sponsor
- Medical University of Warsaw · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The aim of this study was to assess serum N-terminal proBNP (NT-proBNP) in systemic sclerosis patients and to establish whether it reflects the severity of RV overload.
Detailed description
Elevated serum brain natriuretic peptide (BNP) levels released from myocytes of ventricles upon stretch have been found in patients with isolated right ventricular (RV) pressure overload. However, limited data suggest that serum BNP may be elevated in patients with systemic sclerosis (SSc), especially with RV dysfunction. The aim of this study was to assess serum N-terminal proBNP (NT-proBNP) in SSc patients and to establish whether it reflects the severity of RV overload.
Conditions
Timeline
- Start date
- 2006-04-01
- Completion
- 2010-04-01
- First posted
- 2007-03-29
- Last updated
- 2007-03-29
Locations
1 site across 1 country: Poland
Source: ClinicalTrials.gov record NCT00453752. Inclusion in this directory is not an endorsement.