NCT00446875

Analgesic Properties of Oral Sucrose During Immunizations

Efficacy of Oral Sucrose and Maternal Contact During Routine Immunizations in Postnatal Infants

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 98 (actual)
• Sponsor: Milton S. Hershey Medical Center · Academic / Other
• Sex: All
• Age: 3 Months – 11 Months
• Healthy volunteers: Accepted

Summary

The purpose of this study is to examine the analgesic properties of oral sucrose during routine immunizations. Hypothesis: Oral sucrose solution and maternal contact will significantly decrease the objective measures of acute pain during routine immunizations.

Detailed description

The purpose of this study is to examine the analgesic properties of oral sucrose during routine immunizations. Hypothesis: Oral sucrose solution and maternal contact will significantly decrease the objective measures of acute pain during routine immunizations. Acute pain during early life may alter infant pain responses, cognitive development and behavioral outcomes. Infants respond to immunizations with significant pain and distress. This study will examine the analgesic properties of oral sucrose and maternal holding in postnatal infants. Comparison: Administration of oral sucrose, sterile water and maternal contact 2 minutes before routine immunizations.

Conditions

• Procedural Pain

Interventions

Type	Name	Description
OTHER	Administration of oral Sucrose	Participants received oral sucrose 2 minutes prior to the combind DTaP, IPV, and Hep B vaccine.
OTHER	Administration of oral Placebo	Participants received Placebo 2 minutes prior to the combind DTaP, IPV, and Hep B vaccine.

Timeline

• Start date: 2007-01-01
• Primary completion: 2008-05-19
• Completion: 2008-05-19
• First posted: 2007-03-13
• Last updated: 2019-02-15

Locations

1 site across 1 country: United States