Clinical Trials Directory

Trials / Completed

CompletedNCT00440661

Exploration of the Synovial Fluid Inflammation Mediators Under Diacerhein in Knee Osteoarthritis

Exploratory Study of Some Synovial Fluid Inflammation Mediatorsunder Diacerhein in Knee Osteoarthritis Patients. Phase IV Study.

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
96 (estimated)
Sponsor
Laboratoires NEGMA · Industry
Sex
All
Age
45 Years – 80 Years
Healthy volunteers
Not accepted

Summary

Some inflammation mediators, notably IL-1, are implied in the joint degeneration phenomena of osteoarthritis. The aim of this study is to confirm in vivo the favourable effect of diacerhein on IL-1 and also to appreciate its effect on other synovial inflammation mediators.

Conditions

Interventions

TypeNameDescription
DRUGDiacerhein

Timeline

Start date
2007-03-01
Primary completion
2008-10-01
Completion
2008-10-01
First posted
2007-02-27
Last updated
2010-03-04

Locations

1 site across 1 country: Canada

Source: ClinicalTrials.gov record NCT00440661. Inclusion in this directory is not an endorsement.