Clinical Trials Directory

Trials / Terminated

TerminatedNCT00423176

The Study of Nasonex® Compared With Placebo for the Relief of Symptoms Associated With Acute Bacterial Sinusitis When Used With Antibiotics (Study P04824AM3)

Efficacy and Safety of 200mcg BID Mometasone Furoate Nasal Spray (MFNS) Versus Placebo as Adjunctive Treatment to Antibiotics in Relief of Symptoms of Acute Bacterial Sinusitis

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
237 (actual)
Sponsor
Organon and Co · Industry
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of Nasonex® (mometasone furoate nasal spray), when used together with an antibiotic, for the relief of symptoms associated with acute bacterial sinusitis. Efficacy will be based on both subjective (assessment of symptom severity by the patient) and objective measurements (computed tomography \[CT\] imaging of the sinuses).

Conditions

Interventions

TypeNameDescription
DRUGMFNS and antibioticMFNS BID for 29 days plus amoxicillin/clavulanic acid BID for 10 days
DRUGMatching Placebo nasal spray plus antibioticMatching placebo nasal spray BID for 29 days plus amoxicillin/clavulanic acid BID for 10 days

Timeline

Start date
2006-12-01
Primary completion
2008-06-01
Completion
2008-06-01
First posted
2007-01-18
Last updated
2024-05-20
Results posted
2010-06-22

Source: ClinicalTrials.gov record NCT00423176. Inclusion in this directory is not an endorsement.