Trials / Completed
CompletedNCT00380328
HKI-272 Ketoconazole Drug Interaction Study
An Open-label, Randomized, 2-period Crossover, Drug Interaction Study to Evaluate the Potential Pharmacokinetic Interaction Between Multiple Doses of Ketoconazole and a Single Dose of HKI-272 Administered Orally to Healthy Subjects
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 24 (actual)
- Sponsor
- Puma Biotechnology, Inc. · Industry
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
To investigate a potential pharmacokinetic drug interaction between HKI-272 and ketoconazole when co-administered.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | neratinib | HKI-272 |
Timeline
- Start date
- 2006-10-01
- Completion
- 2006-11-01
- First posted
- 2006-09-25
- Last updated
- 2012-05-14
Source: ClinicalTrials.gov record NCT00380328. Inclusion in this directory is not an endorsement.