Trials / Unknown
UnknownNCT00378586
Barrier Function and Production of Inflammatory Cytokines in the Rectal Mucosa in Patients With Septic Shock
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 30 (estimated)
- Sponsor
- Herlev Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Life-threatening infection impairs bloodflow to the gut, thereby causing less delivery of oxygen. This leads to increased formation of different inflammatory and infectious markers. The investigators hypothesize, therefore, that there is a significant difference in the concentrations of inflammatory and infectious markers in the rectal mucosa between patients with septic shock and healthy controls.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Rectal biopsy | Rectal biopsy. |
| PROCEDURE | Measurement of inflammatory markers in the rectal mucosa | IL-6, TNF-alfa. |
| PROCEDURE | Measurement of rectal lactic acid | Equilibrium dialysis. |
Timeline
- Start date
- 2010-01-01
- First posted
- 2006-09-20
- Last updated
- 2009-06-23
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT00378586. Inclusion in this directory is not an endorsement.