NCT00358306

The Role of Endothelium Dysfunction in Progression of CKD (Chronic Kidney Disease) After AKI (Acute Kidney Injury)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 36 (actual)
• Sponsor: University of Alabama at Birmingham · Academic / Other
• Sex: All
• Age: 2 Years – 20 Years
• Healthy volunteers: Accepted

Summary

To understand how AKI (Acute Kidney Injury) leads to chronic kidney disease so therapies can be found to alter the progression of events thereby significantly impacting the long-term outcomes of children who develop AKI.

Detailed description

This research study is designed to study what happens to the kidneys after they have an injury. There is some evidence that even if there appears to be great improvement of kidney function, an injury can put patients at risk for long-term problems with their kidney function and increase their risk to have high blood pressure. We want to collect information from participants to help explain why this injury can cause future problems, including Chronic Kidney Disease (CKD) which may help us prevent these health problems.

Conditions

• Acute Renal Failure
• Chronic Kidney Failure
• Endothelial Dysfunction
• Hemolytic-uremic Syndrome (HUS)

Timeline

• Start date: 2008-04-01
• Primary completion: 2009-07-01
• Completion: 2009-07-01
• First posted: 2006-07-31
• Last updated: 2020-05-14

Locations

1 site across 1 country: United States