NCT00335309

Maxillary Sinus Irrigation in the Management of Chronic Rhinosinusitis

Effectiveness of Maxillary Sinus Saline Irrigation in Conjunction With Systemic Antibiotic Therapy Versus Systemic Antibiotic Therapy Alone in the Management of Chronic Rhinosinusitis, a Prospective Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Ohad Ronen · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the effectiveness of maxillary sinus saline irrigation in conjunction with systemic antibiotic therapy versus systemic antibiotic therapy alone in the management of chronic rhinosinusitis, a prospective randomized controlled trial.

Detailed description

Effectiveness of maxillary sinus saline irrigation in conjunction with systemic antibiotic therapy versus systemic antibiotic therapy alone in the management of chronic rhinosinusitis. A prospective randomized controlled trial is being conducted in Carmel Medical Center, Haifa, Israel. Patients are being randomized into one of two arms. One arm receives sinus irrigation with saline in conjunction with IV antibiotics, the control arm receives the same regimen of IV antibiotics without the sinus irrigation. Quality of life, CT scans and nasal endoscopy parameters are collected before and after treatment.

Conditions

• Sinusitis

Interventions

Type	Name	Description
PROCEDURE	Maxillary Sinus Irrigation	Twice a day irrigation with 100cc saline for 4 days
DRUG	IV Amoxicillin and Clavulanate acid	IV Amoxycillin and Clavulanate 1 Gram TID for 4 days.

Timeline

• Start date: 2005-10-01
• Primary completion: 2013-08-01
• Completion: 2013-08-01
• First posted: 2006-06-09
• Last updated: 2013-10-08

Locations

1 site across 1 country: Israel