Trials / Completed
CompletedNCT00329134
Investigation of the Efficacy of Quinine Sulphate Administered Via Taste-Masked Pellets to Children With Falciparum Malaria
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 56 (estimated)
- Sponsor
- University Ghent · Academic / Other
- Sex
- All
- Age
- 6 Months – 59 Months
- Healthy volunteers
- Not accepted
Summary
No pediatric formulations of quinine exist. Therefore, quinine tablets are broken into 2 or 4 parts, according to the body weight. Based on the body weight, 1/2 or 1/4 a tablet is administered to the child. At this moment, quinine sulphate pellets are developed. These pellets enable an adequate dosing according to the body weight. 56 children with malaria will be dosed every 8 hours during 7 days with 10-15mg/kg body weight.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Administration of quinine sulphate taste-masked pellets |
Timeline
- Start date
- 2006-07-01
- Primary completion
- 2007-05-01
- Completion
- 2007-05-01
- First posted
- 2006-05-24
- Last updated
- 2009-04-17
Locations
1 site across 1 country: Rwanda
Source: ClinicalTrials.gov record NCT00329134. Inclusion in this directory is not an endorsement.