NCT00328900

Measurement of Stress During Anesthesia With "Pain Detector" on Patients Receiving Atropine

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Rikshospitalet University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

24 patients randomly divided into two groups, one of the groups receiving atropine in addition to the planned anaesthesia. Skin conductance parameters to be compared between the two groups.

Detailed description

Skin conductance (SC), in terms of numbers of skin conduction fluctuations (NSCF), amplitude and mean skin conductance level, reflect the activity in the sympathetic postganglionic cholinergic fibers which innervate the palmar and plantar sweat glands. Skin conductance, especially numbers of skin conductance fluctuations, may be a promising tool to monitor anesthesia. Atropine, an anticholinergic agent, acts as an antagonist on the muscarinic receptors of the sweat glands and inhibits their secretion in a dose-dependent way. The aim of this study was to find out to what degree SC is influenced by i.v. administration of atropine. Study hypothesis: SC is not influenced by i.v. administration of atropine.

Conditions

• Hemorrhoids
• Fissure in Ano

Interventions

Type	Name	Description
DRUG	Administration of 0,7 mg of atropine
DEVICE	Measurement of skin conductance with Pain detector

Timeline

• Start date: 2006-01-01
• First posted: 2006-05-24
• Last updated: 2012-06-01

Locations

1 site across 1 country: Norway