Clinical Trials Directory

Trials / Completed

CompletedNCT00319696

Bosentan in Digital Ulcers

Long-term Bosentan Open Label Extension of the AC-052-331 Study in Systemic Sclerosis Patients With Ischemic Digital Ulcers

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
116 (actual)
Sponsor
Actelion · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The aim of the study is to collect long-term efficacy, tolerability and safety data of bosentan in Systemic Sclerosis (SSc) patients suffering from ischemic digital ulcers (DUs).

Conditions

Interventions

TypeNameDescription
DRUGBosentan 62.5 mgBosentan 62.5-mg oral tablets twice daily (b.i.d.) for 4 weeks (initial dose)
DRUGBosentan 125 mgBosentan 125-mg oral tablets administered b.i.d. (target dose)

Timeline

Start date
2004-07-08
Primary completion
2009-01-22
Completion
2009-01-22
First posted
2006-04-27
Last updated
2025-02-04
Results posted
2012-08-08

Source: ClinicalTrials.gov record NCT00319696. Inclusion in this directory is not an endorsement.