NCT00307944

Study of Pantoprazole for Sleepiness Associated With Acid Reflux and Sleep Apnea

Randomized, Placebo-Controlled Trial of Pantoprazole for Sleepiness Associated With Acid Reflux and Obstructive Sleep Disordered Breathing

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 68 (planned)
• Sponsor: University of Cincinnati · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine if using Pantoprazole decreases your daytime sleepiness and improves your reaction time when compared to using a placebo (sugar pill).

Detailed description

Half of the patients enrolled in the study will begin the study taking Pantoprazole. The other half will begin the study taking a placebo (sugar pill). There is an equal chance of being placed in either group. After two weeks, the patients will stop taking their first batch of medication to allow it to completely leave their bodies. Then the patients will begin taking the other medication so that by the end of the study, each patient will have been treated with pantoprazole for two weeks and placebo for two weeks. At the end of each two weeks, patients will be asked to complete questionnaires regarding their daytime sleepiness and reflux symptoms. Patients will also complete reaction time testing as a measure of daytime sleepiness.

Conditions

• Acid Reflux Disease
• Obstructive Sleep Apnea

Interventions

Type	Name	Description
DRUG	Pantoprazole

Timeline

• Start date: 2004-08-01
• Completion: 2006-08-01
• First posted: 2006-03-28
• Last updated: 2007-12-12

Locations

1 site across 1 country: United States