Trials / Terminated
TerminatedNCT00283361
ZP120 Add-on to Furosemide in Treatment of Acute or Sub-Acute Decompensated Heart Failure
A Phase II,Randomized, Double-Blind, Flexible Dose Study of ZP120 I.V. Infusion as Add-On Therapy in Patients With Acute or Sub-Acute Decompensated Chronic Heart Failure NYHA Class III-IV Treated With Furosemide
- Status
- Terminated
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 130 (planned)
- Sponsor
- Zealand Pharma · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The main purpose of this study is to see if the experimental drug ZP120, when given with the approved drug furosemide to patients with acute or sub-acute heart failure, can reduce the amount of fluid in the patients' lungs and make breathing easier.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | ZP120 | |
| PROCEDURE | I.v. catherization | |
| PROCEDURE | 6-minutes walk performance | |
| BEHAVIORAL | Dyspnea severity assessment | |
| PROCEDURE | Blood sampling for laboratory tests | |
| PROCEDURE | ECG | |
| PROCEDURE | Physical examination |
Timeline
- Start date
- 2006-01-01
- Completion
- 2006-12-01
- First posted
- 2006-01-27
- Last updated
- 2007-02-28
Locations
22 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT00283361. Inclusion in this directory is not an endorsement.