Clinical Trials Directory

Trials / Completed

CompletedNCT00272701

Esomeprazole in PPI Failures - IMPROVE

A Randomised, Open, Phase IV, Parallel Group Multicentre Study to Evaluate a Change of Management in Gastroesophageal Reflux Disease (GERD) Patients by Treatment With Esomeprazole 40 mg or Any Other Proton Pump Inhibitor (PPI), After Initial Treatment Failure, in Ordinary Clinical Practice During 4 Weeks.

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
450 (estimated)
Sponsor
AstraZeneca · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess how PPI treated GERD patients with insufficient symptom control will benefit from a change in management by providing a more efficient acid secretion inhibition during 4 weeks, by evaluation of esomeprazole 40 mg compared to pre-study PPI treatment.

Conditions

Interventions

TypeNameDescription
DRUGEsomeprazole
DRUGOther PPI marketed in Sweden

Timeline

Start date
2005-12-01
Completion
2007-02-01
First posted
2006-01-09
Last updated
2009-03-06

Locations

42 sites across 1 country: Sweden

Source: ClinicalTrials.gov record NCT00272701. Inclusion in this directory is not an endorsement.