NCT00252447

Preop Conformal Radiotherapy - Prostate

A Pilot Study of Pre-Operative Conformal Radiotherapy in Patients With Radical Prostatectomy

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 15 (planned)
• Sponsor: University Health Network, Toronto · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Radical prostatectomy and radical radiation therapy remain the standard treatment approaches for patients with clinically localized prostate cancer (T1, T2).Radical prostatectomy is most effective when the disease is organ confined at the time of surgery. However, in many series up to 60% of patients have positive resection margins at the time of surgery and there is evidence to suggest that these patients may not be curable by surgery alone. A number of preoperative clinical variables including clinical stage, serum Prostate Specific Antigen (PSA) and Gleason scorea re helpful in determining the probability of finding organ confined disease at the time of syrgery.

Conditions

• Prostatic Neoplasm

Interventions

Type	Name	Description
PROCEDURE	Pre-Operative Conformal Radiotherapy

Timeline

• Start date: 2000-05-01
• Primary completion: 2009-03-01
• Completion: 2009-03-01
• First posted: 2005-11-11
• Last updated: 2010-08-11

Locations

1 site across 1 country: Canada