Clinical Trials Directory

Trials / Completed

CompletedNCT00243295

Study Evaluating rhMBP-2/CPM in Open Wedge Osteotomies

A Pilot Study to Validate the Feasibility of Injecting and Monitoring Recombinant Human Bone Morphogenetic Protein-2/Calcium Phosphate Matrix (rhBMP-2/CPM) in Subjects With Open Wedge Osteotomies

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
6 (planned)
Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer · Industry
Sex
All
Age
45 Years – 70 Years
Healthy volunteers
Not accepted

Summary

To assess the feasibility of using rhBMP-2/CPM in OWO as a surgical model for pharmacodynamic studies, with assessment of the following parameters: * Injecting the desired volume of rhBMP-2/CPM within the defect * Conducting longitudinal radiographic absorptiometry of the tibial defect in the presence of rhBMP-2/CPM.

Conditions

Interventions

TypeNameDescription
DRUGrhBMP-2/CPM

Timeline

Start date
2003-11-01
Completion
2005-03-01
First posted
2005-10-21
Last updated
2006-10-06

Source: ClinicalTrials.gov record NCT00243295. Inclusion in this directory is not an endorsement.