Trials / Completed
CompletedNCT00230451
Pre-operative Chemotherapy and Radiation Therapy for Esophageal Carcinoma
A Phase II Trial of Preoperative Chemotherapy and Radiation Therapy Followed by Adjuvant Combination Chemotherapy for Patients With Loco-Regional Esophageal Carcinoma
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- University of Michigan Rogel Cancer Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
Surgery (esophagectomy or removal of the esophagus)has been the standard treatment for cancer of the esophagus. However, evidence suggests that preoperative chemotherapy and radiation therapy may add benefit. The purpose of this study is to determine if a treatment program of combined chemotherapy and radiation therapy prior to surgery and chemotherapy after surgery will delay or eliminate recurrence of the cancer.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Radiation | |
| DRUG | Paclitaxel | |
| DRUG | Cisplatin | |
| DRUG | 5-Fluorouracil |
Timeline
- Start date
- 1997-11-01
- Primary completion
- 1999-12-01
- Completion
- 2008-07-01
- First posted
- 2005-09-30
- Last updated
- 2010-01-15
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00230451. Inclusion in this directory is not an endorsement.