NCT00229034

Effect of APC and Epo on the Inflammatory Response During Sepsis

Effect of Activated Protein C and Erythropoietin on the Microvascular Inflammatory Response During Severe Sepsis.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 40 (actual)
• Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

An observational study to determine the effect of APC and Epo in reducing the systemic inflammatory response during severe sepsis.

Detailed description

An observational study to determine the effect of APC and Epo in reducing the systemic inflammatory response during severe sepsis. Patients already prescribed either drug will be enrolled. The microcirculation of the sublingual vascular bed will be observed with a microscope to detect the alterations in the inflammatory response.

Conditions

• Sepsis
• Systemic Inflammation

Timeline

• Start date: 2005-09-01
• Primary completion: 2010-12-01
• Completion: 2011-09-01
• First posted: 2005-09-29
• Last updated: 2017-08-25

Locations

1 site across 1 country: Canada