NCT00227357

The CORE Buprenorphine Project - An HIV Primary Care Program Demonstration

SPNS - An Evaluation of Innovative Methods for Integrating Buprenorphine Opioid Abuse Treatment in HIV Primary Care

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 101 (actual)
• Sponsor: Ruth M. Rothstein CORE Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to develop and evaluate an innovative model of care to better serve patients who are both HIV-infected and opioid-dependent.

Detailed description

Hypothesis: HIV, opioid dependent patients provided agonist therapy at the site of their primary care will have better retention, utilization of services, health, social and quality of care measures and psychiatric treatment outcomes. The Buprenorphine Project is an examination of two methods of service delivery. The purpose of this study is to assess the feasibility, cost and effectiveness of an intervention designed to integrate buprenorphine treatment for opioid dependence into HIV primary care at the CORE Center. For this project we will provide buprenorphine to 60 opioid dependent patients at any one time and will compare this on-site treatment group to 60 opioid dependent HIV+ patients who select off-site methadone or no agonist treatment at the time of enrollment.

Conditions

• HIV Infections
• AIDS
• Opiate Dependence
• Post-Traumatic Stress Disorders

Interventions

Type	Name	Description
DRUG	On-site - buprenorphine/naloxone (Suboxone)	Tablet, sub-lingual, 8/2 mg, 1-3 daily
DRUG	Off-site - methadone or no agonist

Timeline

• Start date: 2005-07-01
• Primary completion: 2008-12-01
• Completion: 2008-12-01
• First posted: 2005-09-28
• Last updated: 2010-06-07

Locations

1 site across 1 country: United States