Trials / Unknown
UnknownNCT00221832
Molecular Genetic Screening and Identification of Congenital Arrhythmogenic Diseases
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 300 (estimated)
- Sponsor
- Heidelberg University · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
The aim of this study is the identification of familial congenital arrhythmogenic disorders and their clinical follow-up.
Detailed description
Molecular genetic screening in patients with: * supraventricular * ventricular arrhythmia * syncopes of unknown origin and/or suspicion of an arrhythmogenic origin * family members of patients with sudden cardiac death and aborted sudden cardiac death Examination of patients includes routine testing like electrocardiogram (ECG), sequential ECGs, exercise testing, invasive electrophysiological stimulation, cardiac magnetic resonance imaging, intravenous drug challenge for identification/exclusion of eg Brugada syndrome. Examples are patients with Long QT Syndrome, Short QT Syndrome, Brugada Syndrome, familial atrial fibrillation, WPW-syndrome, arrhythmias due to familial hypertrophic cardiomyopathy or arrhythmogenic right ventricular dysplasia. Blood samples are taken for further molecular genetic screening.
Conditions
Timeline
- Start date
- 2003-10-01
- Completion
- 2011-12-01
- First posted
- 2005-09-22
- Last updated
- 2010-01-13
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT00221832. Inclusion in this directory is not an endorsement.