NCT00217087

Endoscopic Therapy of Early Cancer in Barretts Esophagus

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 73 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is being done to see if treatment for esophageal cancer can be done using endoscopy for patients ineligible for surgical or radiological therapy. The standard method of treating this type of cancer is surgical removal of the esophagus. The study will determine if removing just the cancer with endoscopy is enough treatment or if the addition of another treatment called photodynamic therapy (treatment with a red light and a drug called sodium porfimer) is needed.

Detailed description

Participant visit requirements: Screening visit which will last 1 - 2 days, if assigned to photodynamic therapy, there will be a 3 day visit for treatment. Participants must return for a 1 day visit every three months for one year.

Conditions

• Early Stage Esophageal Adenocarcinoma
• Barrett Esophagus

Interventions

Type	Name	Description
PROCEDURE	Endoscopic Mucosal Resection	Endoscopic mucosal resection at time of endoscopy if indicated.
PROCEDURE	Photodynamic Therapy	Porfimer sodium 2mg/kg

Timeline

• Start date: 2005-09-01
• Primary completion: 2012-06-01
• Completion: 2012-06-01
• First posted: 2005-09-22
• Last updated: 2015-12-24
• Results posted: 2015-09-25

Locations

1 site across 1 country: United States