NCT00204412

Exercise and Flax-Based Nutritional Supplementation for Lowering Cholesterol

Effectiveness of Flax Lignan and Exercise Training for Improving Lipid Profiles

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: University of Saskatchewan · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of our study is to use a flaxseed-based nutritional supplement in combination with exercise training (walking) for improving cholesterol levels. We hypothesize that exercise training will improve cholesterol profile and that adding supplementation with a flaxseed nutritional supplement will further improve cholesterol profile.

Detailed description

Flax supplementation and exercise training each have small beneficial effects for improving blood lipid profile and reducing cardiovascular disease risk. Flax lignan, a phytoestrogen found in flaxseed is thought to be the active compound responsible for the cholesterol-lowering effect of flaxseed. Our purpose is to combine an exercise training program (walking) with flax lignan supplementation for improving blood lipid profile. Comparisons: Walking (6 days per week) plus flax lignan (500 mg per day) compared to walking plus placebo.

Conditions

• Metabolic Syndrome
• Osteoporosis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Flax lignan	543 mg SDG per day
BEHAVIORAL	Exercise (walking)	walking 45 minutes per day 5 days per week

Timeline

• Start date: 2005-03-01
• Completion: 2006-03-01
• First posted: 2005-09-20
• Last updated: 2007-11-05

Locations

1 site across 1 country: Canada