NCT00188318

Hardwins - Squamous Cell Carcinoma Head & Neck (Surgery/RT)

A Phase II Study of Hyperfractionated Accelerated Radiotherapy Delivered With Integrated Neck Surgery for Node-positive Cases in Squamous Cell Carcinoma of the Head and Neck

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 169 (actual)
• Sponsor: University Health Network, Toronto · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is examining the effects of increasing the dose of radiation given to treat head and neck cancer. Radiation doses to the primary cancer are higher than usually given; lymph glands of the neck will also be treated at a lower dose. Surgery on the lymph glands my be necessary in the future. Radiation treatments given in small fractions twice a day allows a higher dose to be delivered than if the treatment was given once a day. This study will enroll patients at three sequential increasing dose levels. Approximately 40 patients will be enrolled at each dose level.

Conditions

• Carcinoma, Squamous Cell

Interventions

Type	Name	Description
PROCEDURE	hyperfractionated accelerated radiotherapy

Timeline

• Start date: 1998-06-01
• Primary completion: 2010-05-01
• Completion: 2010-05-01
• First posted: 2005-09-16
• Last updated: 2016-02-09

Locations

1 site across 1 country: Canada