NCT00182195

Lung Open Ventilation to Decrease Mortality in the Acute Respiratory Distress Syndrome

A Randomized Trial of a Lung-Open Ventilation Strategy in Acute Lung Injury

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 980 (planned)
• Sponsor: Hamilton Health Sciences Corporation · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A multinational, randomized trial comparing two lung protecting strategies of respiratory life support among critically ill patients with severe lung injury.

Detailed description

To compare an innovative Lung Open Ventilation strategy with a proven low tidal volume strategy, hypothesizing that the Lung Open Ventilation strategy may reduce mortality, other organ dysfunction, and the duration of mechanical ventilation, intensive care, and hospital stay.

Conditions

• Acute Respiratory Distress Syndrome

Interventions

Type	Name	Description
PROCEDURE	Control Ventilation Strategy

Timeline

• Start date: 2000-08-01
• Completion: 2006-03-01
• First posted: 2005-09-16
• Last updated: 2007-04-23

Locations

1 site across 1 country: Canada