Trials / Recruiting
RecruitingNCT00181259
Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism
In Vivo Cardiac Metabolism in Normal, Ischemic, and Cardiomyopathic Patients During Rest and Stress
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 500 (estimated)
- Sponsor
- Johns Hopkins University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The metabolism of the heart provides the chemical energy needed to fuel ongoing normal heart contraction. Magnetic resonance spectroscopy is a technique used in a MRI scanner that can be used to measure and study heart metabolism directly but without blood sampling or obtaining tissue biopsies. One of the hypotheses this study aims to investigate is whether energy metabolism is reduced in heart failure and whether that contributes to the poor heart function.
Detailed description
This study uses magnetic resonance (MR) spectroscopy to study heart metabolism and function in normal subjects and patients with left ventricular hypertrophy, dilated cardiomyopathy, and those with coronary artery disease.
Conditions
Timeline
- Start date
- 1988-01-01
- Primary completion
- 2027-08-01
- Completion
- 2028-08-01
- First posted
- 2005-09-16
- Last updated
- 2026-03-09
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00181259. Inclusion in this directory is not an endorsement.