Trials / Completed
CompletedNCT00180908
Comparison of High-Dose Methotrexate (HDM) Plus Doxorubicin to HDM Plus Etoposide-Ifosfamide in Osteosarcoma Children
SFOP-OS94: Multicentric Randomised Phase III Trial Comparing Efficacy of Preoperative High-Dose Methotrexate Plus Doxorubicin to Efficacy of High-Dose Methotrexate Plus Etoposide and Ifosfamide, in Children and Adolescents Osteosarcoma
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 226 (planned)
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris · Academic / Other
- Sex
- All
- Age
- 20 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to compare two preoperative chemotherapy regimens based on high-dose methotrexate courses given alternately either with doxorubicin or with etoposide-ifosfamide.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Etoposide, Ifosfamide, Methotrexate | |
| DRUG | Doxorubicin, Methotrexate |
Timeline
- Start date
- 1994-06-01
- First posted
- 2005-09-16
- Last updated
- 2005-09-16
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT00180908. Inclusion in this directory is not an endorsement.