NCT00169221

Post-operative Radiotherapy With Cisplatin Alone or in Combination With Iressa in Upper Aerodigestive Tract Carcinomas

CARISSA Trial - Multicenter Randomized Phase II Trial Comparing Post-operative Radiotherapy and Cisplatin Alone or in Combination With the EGFR Inhibitor ZD 1839 (Iressa) in Upper Aerodigestive Tract Carcinomas

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 54 (actual)
• Sponsor: Groupe Oncologie Radiotherapie Tete et Cou · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This trial will be an open multicentric randomized phase II study comparing post-operative radiotherapy + cisplatin associated or not with Iressa in upper aerodigestive tract carcinomas.

Conditions

• Head and Neck Cancer

Interventions

Type	Name	Description
DRUG	Iressa (Gefitinib)	postoperative chemoradiotherapy with cisplatin + gefitinib
RADIATION	chemoradiotherapy with cisplatin	postoperative chemoradiotherapy with cisplatin

Timeline

• Start date: 2005-09-01
• Primary completion: 2009-07-01
• Completion: 2011-07-01
• First posted: 2005-09-15
• Last updated: 2011-11-15

Locations

1 site across 1 country: France