Trials / Completed
CompletedNCT00168467
The Effects of Ramipril on Clinical Symptoms in Patients With Peripheral Arterial Disease
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 40 (planned)
- Sponsor
- Baker Heart Research Institute · Academic / Other
- Sex
- All
- Age
- 70 Years
- Healthy volunteers
- Not accepted
Summary
One important clinical challenge in older individuals is maintaining mobility in the absence of pain. Peripheral arterial disease affects up to 12% of adults over 50 and impairs quality of life due to intermittent claudication causing pain and limiting mobility. Conventional therapies have only modest effect in improving symptoms. The investigators hypothesise that angiotensin converting enzyme inhibition (with ramipril), which causes arterial vasodilation, also improves clinical symptoms in patients with peripheral arterial disease.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Ramipril |
Timeline
- First posted
- 2005-09-15
- Last updated
- 2009-01-29
Locations
1 site across 1 country: Australia
Source: ClinicalTrials.gov record NCT00168467. Inclusion in this directory is not an endorsement.