NCT00159146

Trial of Pindolol Augmentation in Venlafaxine Treated Patients With Major Depression

A Short Term Double Blind Randomised Trial of Pindolol Augmentation in Venlafaxine Treated Patients With Major Depression

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: Hillerod Hospital, Denmark · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study investigates the hypothesis that pindolol can accelerate the response to antidepressants in patients with major depression treated with venlafaxine.

Detailed description

Antidepressant therapy has a delayed onset of action of 4-6 weeks. Pindolol has in some studies shown an accelerating effect. In this study we investigate the effect of 20 mg of pindolol retarded formulation in combination with Venlafaxine compared to placebo Pindolol and Venlafaxine for a duration of 19 days. Effect is measured by the Hamilton Depression rating Scale and the Preskorn Scale (self-rating).

Conditions

• Major Depression

Interventions

Type	Name	Description
DRUG	Pindolol and venlafaxin	pindolol 20 mg and venlafaxin 150 mg

Timeline

• Start date: 2002-08-01
• Completion: 2007-09-01
• First posted: 2005-09-12
• Last updated: 2007-12-27

Locations

1 site across 1 country: Denmark