Clinical Trials Directory

Trials / Completed

CompletedNCT00158067

Study of an External Responsive Neurostimulator System on Epileptiform Activity

Automated Response to Spontaneous Epileptiform Activity Using the External Responsive Neurostimulator (eRNS) System Clinical Investigation

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
150 (estimated)
Sponsor
NeuroPace · Industry
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

This feasibility clinical investigation is designed to demonstrate that the NeuroPace external Responsive Neurostimulator (model eRNS-300) can safely deliver responsive electrical stimulation automatically to affect epileptiform activity. The eRNS-300 is based on an implantable neurostimulator that has been adapted for acute, external use in a hospital setting.

Detailed description

The Automated Response to Spontaneous Epileptiform Activity using the External Responsive Neurostimulator (eRNS) system clinical investigation involves subjects who are undergoing intracranial monitoring for the evaluation of epilepsy surgery and who are being monitored in the hospital's epilepsy monitoring unit. During the subject's participation, at the discretion of the investigator, the subject will be connected to the eRNS. The eRNS is an investigational device that attaches to standard intracranial electrode monitoring equipment to monitor the subject's seizure activity. It is anticipated that the subject may be connected to the eRNS for a period of time extending from one day to a few weeks. After the subject has enough seizures to complete their evaluation for epilepsy surgery, the physician may enable the responsive stimulation settings for the eRNS. The subject's participation in the clinical investigation will be complete prior to the removal of their intracranial electrodes.

Conditions

Interventions

TypeNameDescription
DEVICEexternal Responsive Neurostimulator (eRNS) System

Timeline

Start date
2002-03-01
Primary completion
2007-04-01
Completion
2008-03-01
First posted
2005-09-12
Last updated
2010-08-26

Locations

5 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00158067. Inclusion in this directory is not an endorsement.