Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT00151385

Study Evaluating Inhibitor Specificity in Hemophilia A

A Multicenter Study to Describe the Immunogenic Epitope(s) of Factor VIII in Previously Treated Patients With Congenital Hemophilia A Who Develop De Novo Factor VIII Inhibitors While Receiving Factor VIII Infusion Therapy.

Status
Withdrawn
Phase
Phase 4
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer · Industry
Sex
All
Age
Healthy volunteers
Not accepted

Summary

This investigation will utilize a systematic determination of anti-FVIII antibody specificity in PTPs (\> 50 ED) with hemophilia A who have developed inhibitors in response to treatment with any FVIII product(s). A group of patients with hemophilia A, who have no evidence of current or prior FVIII inhibitor will be included for comparison. The objective of this study is to describe the patterns of antibodies and associated epitopes in the study population.

Conditions

Interventions

TypeNameDescription
PROCEDUREsingle blood draw

Timeline

Start date
2005-11-01
Completion
2007-10-01
First posted
2005-09-08
Last updated
2012-06-28

Locations

23 sites across 7 countries: United States, Belgium, France, Germany, Italy, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT00151385. Inclusion in this directory is not an endorsement.