Trials / Completed
CompletedNCT00138684
Cytochrome P450 2E1 and Iron Overload
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 50 (actual)
- Sponsor
- Rennes University Hospital · Academic / Other
- Sex
- Male
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
The aim of the study is to determine, in patients presenting hepatic iron overload (genetic haemochtomatisis or dysmetabolic iron overload syndrome), the effects of venesection therapy on cytochrome P450 2E1 activity by comparing the rates of metabolization of chlorzoxazone before and after venesection.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | venesection | Venesection therapy is realised every 7 - 14 days until iron desaturation completion. |
Timeline
- Start date
- 2003-09-01
- Primary completion
- 2005-12-01
- Completion
- 2006-02-01
- First posted
- 2005-08-30
- Last updated
- 2012-05-21
Locations
2 sites across 1 country: France
Source: ClinicalTrials.gov record NCT00138684. Inclusion in this directory is not an endorsement.