NCT00135122

Prednisolone in the Treatment of Withdrawal Headache in Probable Medication Overuse Headache

Medication Overuse Headache: A Randomised Double Blind Study of Prednisolone or Placebo in Withdrawal Therapy (Phase 3), and a Randomised 1 Year Follow up by Neurologist or General Physician After Successful Withdrawal Therapy

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Sorlandet Hospital HF · Other Government
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether prednisolone is more effective than placebo in the first six days after initiation of medication withdrawal therapy for a medication overuse headache. Another purpose is to study whether patients followed by a neurologist 1 year after withdrawal do better than patients followed by a general practitioner.

Detailed description

Data published BoeMG,Mygland A,Salvesen R; Neurology 2007 Jul 3;69(1):26-31

Conditions

• Headache

Interventions

Type	Name	Description
DRUG	prednisolone	Prednisolone 60mg day 1 and 2 , 40mg day 3 and 4 , 20mg day 5 and 6

Timeline

• Start date: 2003-09-01
• Primary completion: 2007-01-01
• Completion: 2007-01-01
• First posted: 2005-08-25
• Last updated: 2008-09-12

Locations

1 site across 1 country: Norway