NCT00120211

Trial of Five Versus Six Fractions Per Week for Head and Neck Cancer

Phase III Trial of Five Versus Six Fractions Per Week for Head and Neck Cancer

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 855 (actual)
• Sponsor: International Atomic Energy Agency · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This trial compares the use of 6 fractions versus the standard 5 fractions of radiotherapy used in the treatment of head and neck cancer.

Detailed description

The purpose of this trial is to study the clinical effects of increasing the weekly fraction number for locally advanced head and neck cancers by a multi-institutional prospective randomised trial. The primary endpoint is to clarify whether a six fraction per week protocol has a greater effect on the survival, as compared to the conventional five fraction per week protocol.

Conditions

• Head and Neck Cancer

Interventions

Type	Name	Description
RADIATION	Accelerated Radiotherapy Fractionation	Radiation Therapy 6 fractions per week
RADIATION	Accelerated Radiotherapy Fractionation	Radiotherapy 5 fractions per week

Timeline

• Start date: 1998-09-01
• Primary completion: 2006-05-01
• Completion: 2006-05-01
• First posted: 2005-07-15
• Last updated: 2011-10-13