Clinical Trials Directory

Trials / Completed

CompletedNCT00116701

Treatment for Subjects With Chronic Kidney Disease Receiving Haemodialysis

A Study to Evaluate the Efficacy of Converting From Intravenous or Subcutaneous rHuEPO to Intravenous Darbepoetin Alfa (Aranesp®) in Subjects With Chronic Kidney Disease Receiving Haemodialysis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
200 (planned)
Sponsor
Amgen · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Treatment period 1:To demonstrate that switching HD subjects with a baseline haemoglobin (Hb) ≥ 10 g/dL and ≤ 13 g/dL from either subcutaneous (SC) or intravenous (IV) rHuEPO to IV darbepoetin alfa results in a mean Hb \> 11 g/dL. Treatment Period 2:To demonstrate that switching subjects with a Hb \> 11 g/dL and ≤ 13 g/dL from once weekly IV darbepoetin alfa to once every 2 weeks (Q2W) maintains the mean Hb at \> 11 g/dL.

Conditions

Interventions

TypeNameDescription
DRUGAranesp®

Timeline

Start date
2005-05-01
First posted
2005-07-01
Last updated
2008-05-05

Source: ClinicalTrials.gov record NCT00116701. Inclusion in this directory is not an endorsement.