Trials / Completed
CompletedNCT00112034
AVONEX® Combination Trial - "ACT"
A Multi-Center, Randomized, Blinded, Parallel-Group Study of AVONEX Compared With AVONEX in Combination With Oral Methotrexate, Intravenous Methylprednisolone, or Both in Subjects With Relapsing Remitting MS Who Have Breakthrough Disease on AVONEX Monotherapy.
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 350 (planned)
- Sponsor
- Biogen · Industry
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine the efficacy and safety of combination therapy with AVONEX plus low dose oral methotrexate (MTX), every other month courses of intravenous methylprednisolone (IVMP), or both in patients with continued disease activity on AVONEX monotherapy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Methotrexate | |
| DRUG | IV methylprednisolone |
Timeline
- Start date
- 2003-06-01
- Primary completion
- 2006-06-01
- Completion
- 2007-05-01
- First posted
- 2005-05-30
- Last updated
- 2008-05-09
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00112034. Inclusion in this directory is not an endorsement.