Trials / Completed
CompletedNCT00110604
The Effect of Folic Acid on Atherosclerosis, Cognitive Performance and Hearing
The Folic Acid and Carotid Intima-Media Thickness (FACIT) Study: A Randomized Controlled Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 835 (planned)
- Sponsor
- Wageningen University · Academic / Other
- Sex
- All
- Age
- 50 Years – 70 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to determine if folic acid supplementation can slow down atherosclerotic progression, age-related cognitive decline and age-related hearing loss.
Detailed description
Low levels of B vitamins, in particular folate, and high levels of plasma total homocysteine, have been associated with a variety of age-related diseases and disorders, including cardiovascular disease, dementia and hearing impairment. Extra folate, for example in the form of folic acid, is known to decrease the concentrations of plasma total homocysteine. We examined whether 0.8 mg/d folic acid could slow down atherosclerotic progression and the above mentioned age-related processes.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | folic acid (0.8 mg) |
Timeline
- Start date
- 2000-09-01
- Completion
- 2004-12-01
- First posted
- 2005-05-11
- Last updated
- 2008-12-31
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT00110604. Inclusion in this directory is not an endorsement.