Trials / Completed
CompletedNCT00108173
Brain Reaction to Treatment of Nicotine Dependence
Neural Substrates of Treatment for Nicotine Dependence
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 104 (actual)
- Sponsor
- US Department of Veterans Affairs · Federal
- Sex
- All
- Age
- 21 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of the study was to determine how the treatments for cigarette craving work. Hypothesis: During exposure to cigarette-related cues, heavy smokers will have greater reductions in regional brain activation from before to after both forms of active treatments than from before to after placebo.
Detailed description
PET and fMRI scanning were used to examine brain activity and activation in cigarette smokers in response to cigarette-related cues.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Zyban |
Timeline
- Start date
- 2002-10-01
- Primary completion
- 2007-04-01
- Completion
- 2011-06-01
- First posted
- 2005-04-15
- Last updated
- 2013-04-09
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00108173. Inclusion in this directory is not an endorsement.