Trials / Completed
CompletedNCT00092677
An Investigational Drug on Clinical Outcomes in Patients With Aortic Stenosis (Narrowing of the Major Blood Vessel of the Heart)(MK-0653A-043 AM4)(COMPLETED)
A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Effects of Ezetimibe + Simvastatin on Clinical Outcomes in Patients With Aortic Stenosis
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 1,873 (actual)
- Sponsor
- Organon and Co · Industry
- Sex
- All
- Age
- 45 Years – 85 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to evaluate whether treatment with an investigational drug as compared to placebo will reduce the risk of major cardiovascular events in patients with aortic stenosis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | ezetimibe (+) simvastatin | Duration of Treatment: 4 years |
| DRUG | Comparator: Placebo | matching Placebo |
Timeline
- Start date
- 2001-01-01
- Primary completion
- 2008-04-01
- Completion
- 2008-04-01
- First posted
- 2004-09-28
- Last updated
- 2024-05-16
- Results posted
- 2009-05-27
Source: ClinicalTrials.gov record NCT00092677. Inclusion in this directory is not an endorsement.