NCT00075049

Safety and Efficacy Study of RTS,S AS02A/AS01B Vaccine to Prevent Malaria

Dbl-Blind, Rand Phase 1/2a Human Challenge Study, to Eval Safety, Reactogenicity, Immunogenicity and Preliminary Efficacy After Sporozoite Challenge/Rechallenge of Vaccines Containing RTS,S

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 104 (planned)
• Sponsor: U.S. Army Medical Research and Development Command · Federal
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This is a double blinded study where 2 test vaccines will be evaluated to see if they protect persons who have never had malaria against malaria infection when bitten by mosquitoes.

Conditions

• Malaria

Interventions

Type	Name	Description
BIOLOGICAL	RTS,S with AS02A/AS01B adjuvant

Timeline

• Start date: 2003-12-01
• Primary completion: 2006-01-01
• Completion: 2006-01-01
• First posted: 2004-01-01
• Last updated: 2014-08-21

Locations

1 site across 1 country: United States