Trials / Completed
CompletedNCT00043381
Decitabine Versus Supportive Care in Adults With Advanced-stage MDS
A Randomized, Open-label, Phase III Trial of Decitabine (5-aza-2'Deoxycytidine) Versus Supportive Care in Adults With Advanced-stage Myelodysplastic Syndrome
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 160 (planned)
- Sponsor
- Astex Pharmaceuticals, Inc. · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To compare the safety and efficacy profiles of decitabine to those of supportive care in adults with advanced-stage myelodysplastic syndrome (MDS)
Detailed description
This experimental (investigational) study is intended to answer the question of whether decitabine is any better than supportive care alone in delaying progression (worsening) of the disease, prolonging survival or improving the overall quality of life for MDS patients who are not candidates for bone marrow transplant (BMT).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | decitabine (5-aza-2'deoxycytidine) |
Timeline
- Start date
- 2001-04-01
- Primary completion
- 2002-11-01
- Completion
- 2003-04-01
- First posted
- 2002-08-12
- Last updated
- 2024-08-02
Locations
24 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT00043381. Inclusion in this directory is not an endorsement.