Clinical Trials Directory

Trials / Completed

CompletedNCT00032786

Safety and Efficacy of Natalizumab in the Treatment of Crohn's Disease

A Phase 3, International, Multicenter, Double-blind, Placebo-controlled Study of the Efficacy, Safety, and Tolerability of Intravenous Antegren (Natalizumab) in Maintaining Clinical Response and Remission in Subjects With Crohn's Disease

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
Sponsor
Biogen · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the safety and efficacy of natalizumab in individuals diagnosed with moderate to severely active Crohn's disease. It is thought that natalizumab may stop the movement of certain cells, known as white blood cells, into bowel tissue. These cells are thought to cause damage in the bowel leading to the symptoms of Crohn's disease.

Conditions

Interventions

TypeNameDescription
DRUGnatalizumab

Timeline

Start date
2002-03-01
Primary completion
2004-03-01
Completion
2004-03-01
First posted
2002-04-04
Last updated
2016-06-16

Source: ClinicalTrials.gov record NCT00032786. Inclusion in this directory is not an endorsement.